linda richards lab

Linda Richards (July 27, 1841 — April 16, 1930) In 1872 Linda Richards became the first student to enroll a brand new course of study: nurse training. Friocourt, François, Kozulin, Peter, Belle, Morgane, Suárez, Rodrigo, Di‐Poï, Nicolas, Richards, Linda J., Giacobini, Paolo and Chédotal, Alain (2019). Here’s a presentation of the results. Preprint available at www.biorxiv.org/content/10.1101/2020.08.03.233593v1. The consortium brings together clinicians and scientists working to identify the causes of developmental brain disorders and how best to provide support and care for affected individuals and their families. Shared and differential features of Robo3 expression pattern in amniotes. (2016) Axonal Guidance: Making Connections. (2003) Slit2 guides both precrossing and postcrossing callosal axons at the midline in vivo. Journal of Neuroscience, 23 22: 8176-8184. Zorana Lynton is an MD/PhD student at The University of Queensland and Queensland Brain Institute under the supervision of Dr. Laura Fenlon and Prof. Linda Richards. (2015) Investigating early formation of the cerebral cortex by in utero electroporation - methods and protocols. In particular, Richards studies how neurons from one brain hemisphere grow across the midline and find their target in the opposite hemisphere. We have generated a number of animal models of Nfi gene mis-expression to determine the function of NFI genes in brain cancer. (2002) Axonal pathfinding mechanisms at the cortical midline and in the development of the corpus callosum. Brazilian Journal of Medical And Biological Research, 35 12: 1431-1439. doi:10.1590/S0100-879X2002001200004, Surrounded by slit - How forebrain commissural axons can be led astray, Richards, LJ (2002) Surrounded by slit - How forebrain commissural axons can be led astray. Neuron, 33 2: 153-155. doi:10.1016/S0896-6273(02)00566-4, A role for cingulate pioneering axons in the development of the corpus callosum, Rash, B. G. and Richards, L. J. Linda Ellison. She earned it in 1873 and the proof of her graduation is now displayed in the Smithsonian Institution in Washington. In his second postdoctoral position, with Prof. Linda Richards at the Queensland Brain Institute at The University of Queensland, his work focussed on understanding the molecular mechanisms of neural progenitor cell specification in the developing cerebral cortex. Take a look inside the Nursing Lab … (2008) Growth cone chemotaxis. Trends in Neurosciences, 31 2: 90-98. doi:10.1016/j.tins.2007.11.008, Nuclear Factor I Gene Expression in the Developing Forebrain, Plachez, Celine, Lindwall, Charlotta, Sunn, Nana, Piper, Michael, Moldrich, Randal X., Campbell, Christine E., Osinski, Jason M., Gronostajski, Richard M. and Richards, Linda J. Transcriptional regulation of intermediate progenitor cell generation during hippocampal development, Harris, Lachlan, Zalucki, Oressia, Gobius, Ilan, McDonald, Hannah, Osinki, Jason, Harvey, Tracey J., Essebier, Alexandra, Vidovic, Diana, Gladwyn-Ng, Ivan, Burne, Thomas H., Heng, Julian I., Richards, Linda J., Gronostajski, Richard M. and Piper, Michael (2016) Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development, 143 24: 4620-4630. doi:10.1242/dev.140681, Astroglial-mediated remodeling of the interhemispheric midline is required for the formation of the corpus callosum, Gobius, Ilan, Morcom, Laura, Sua´rez, Rodrigo, Bunt, Jens, Bukshpun, Polina, Reardon, William, Dobyns, William B., Rubenstein, John L.R., Barkovich, James, Sherr, Elliott H. and Richards, Linda J. View the profiles of professionals named "Linda Richards" on LinkedIn. Linda Richards Nursing Instructor - Nursing Lab Coordinator at Brown Mackie College Lenexa, Kansas Higher Education (2018) Transcriptional control of long-range cortical projections. Current Opinion in Neurobiology 53:57-65 doi.org/10.1016/j.conb.2018.05.005. (2001) A role for cingulate pioneering axons in the development of the corpus callosum. Journal of Comparative Neurology, 434 2: 147-157. doi:10.1002/cne.1170, Cortical axon guidance by the glial wedge during the development of the corpus callosum. Research. Linda Richards, Actress: Survivors: Sophie's story. View all Publications . (2014) Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum.Neuron, 82 6: 1289-1298. doi:10.1016/j.neuron.2014.04.040, Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation, Srivatsa, Swathi, Parthasarathy, Srinivas, Britanova, Olga, Bormuth, Ingo, Donahoo, Amber-Lee, Ackerman, Susan L., Richards, Linda J. and Tarabykin, Victor (2014) Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation. Nature Communications, 5 . Ivic, L, Pyrski, MM, Margolis, JW, Richards, LJ, Firestein, S and Margolis, FL (2000) Adenoviral vector-mediated rescue of the OMP-null phenotype in vivo. Nature Neuroscience, 3 11: 1113-1120. Interpreting these … View Linda Richards’ profile on LinkedIn, the world’s largest professional community. (2009) Nuclear Factor One Transcription Factors in CNS Development. Molecular Neurobiology, 39 1: 10-23. doi:10.1007/s12035-008-8048-6, Specific glial populations regulate hippocampal morphogenesis, Barry, Guy, Michael Piper, Lindwall, Charlotta, Moldrich, Randal, Mason, Sharon, Little, Erica, Sarkar, Anindita, Tole, Shubha, Gronostajski, Richard M. and Richards, Linda J. After obtaining her PhD from WEHI, Linda Richards began her postdoctoral training at the Salk Institute of Biological Studies, in the laboratory of Professor Dennis O'Leary. Edwards T.J., Fenlon L.R., Dean R.J., Bunt J., Sherr E.H. and Richards L.J. Inside your nostrils, there are tiny things called neurons that “talk” to each other using electrical messages. Her laboratory team strives to understand how the brain forms during development and how these processes are disrupted causing human developmental brain disorders and … There are 400+ professionals named "Linda Richards", who use LinkedIn to exchange information, ideas, and opportunities. Publisher: Springer US. (2011) Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum. The Journal of Comparative Neurology, 519 17: 3532-3548. doi:10.1002/cne.22721, Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus, Subramanian, Lakshmi, Sarkar, Anindita, Shetty, Ashwin S., Muralidharan, Bhavana, Padmanabhan, Hari, Piper, Michael, Monuki, Edwin S., Bach, Ingolf, Gronostajski, Richard M., Richards, Linda J. and Tole, Shubha (2011) Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus. Proceedings of the National Academy of Sciences of the United States of America, 108 27: E-265-E-274. (2019-2021) NHMRC Project Grant, Normal and abnormal development of brain wiring and its impact on brain function Nuclear factor one (NFI) genes have been implicated in brain cancer and in glial development. In 2001 the great Grandson of founder Thomas. (2017) Development of body, head and brain features in the Australian fat-tailed dunnart (Sminthopsis crassicaudata; Marsupialia: Dasyuridae); A postnatal model of forebrain formation. (2017–2020) NHMRC Project Grant, Neural circuits that mediate fear extinction She will take the helm Jan. 1. Studying synaptic plasticity and learning, Podcast: fish eyes the window to the brain, Podcast: mysteries of the corpus callosum, Podcast: the most aggressive cancer in the brain, Podcast: using brain imaging to diagnose mental illness, Podcast: curing schizophrenia, from lab to clinic, Podcast: using deep brain stimulation treat Parkinson’s disease, Podcast: coral bleaching in the Great Barrier Reef, Podcast: the curious link between vitamin D and schizophrenia, Podcast: Alzheimer's disease, a family perspective. Chen K-S., Harris L., Lim J.W.C., Harvey T., Piper M., Gronostajski R., Richards L.J. (2019) Responsible innovation in neurotechnology enterprises, OECD Science, Technology and Industry Working Papers, No. Brain cancer is a significant health problem in Australia. Whenever we smell something, our nose and brain work together to make sense of hundreds of very tiny invisible particles, known as molecules or chemicals, that are floating in the air. The lab utilises both mouse and human tissue in its projects and applies the results to identifying the basis of agenesis of the corpus callosum, a condition that occurs in more than 300 different human congenital syndromes. She is a Fellow of both the Australian Academy of Science and the Australian Academy of Health and Medical Sciences and is a National Health and Medical Research Council Principal Research Fellow. (2011) Cyclic nucleotide-dependent switching of mammalian axon guidance depends on gradient steepness. Molecular and Cellular Neuroscience, 47 1: 45-52. doi:10.1016/j.mcn.2011.02.012, An MRI-based atlas and database of the developing mouse brain, Chuang, Nelson, Mori, Susumu, Yamamoto, Akira, Jiang, Hangyi, Ye, Xin, Xu, Xin, Richards, Linda J., Nathans, Jeremy, Miller, Michael I., Toga, Arthur W., Sidman, Richard L. and Zhang, Jiangyang (2011) An MRI-based atlas and database of the developing mouse brain. NeuroImage, 54 1: 80-89. doi:10.1016/j.neuroimage.2010.07.043, Molecular regulation of the developing commissural plate, Moldrich, Randal X., Gobius, Ilan, Pollak, Thomas, Zhang, Jiangyang, Ren, Tianbo, Brown, Lucia, Mori, Susumu, Romero, Camino De Juan, Britanova, Olga, Tarabykin, Victor and Richards, Linda J. Linda. Publisher: Elsevier. and Bunt J. Magnetic Resonance Imaging – diffusion tensor imaging (human and animal). The Journal of Comparative Neuroloy doi: 10.1002/cne.24648. Home; Clients/Pubs; Experience; Awards; About Me; Contact. Our historic Credentials. Callosal agenesis and congenital mirror movements: clinical, imaging and neuropsychological outcomes associated with DCC mutations. Bartlett P.F., Richards L.J., Kilpatrick T.J., Talman P.S., Bailey K., Brooker G., Dutton R., Koblar S., Nurcombe V., Ford M., et al. Linda Stevenson. Development of the perforating pathway: An ipsilaterally projecting pathway between the medial septum/diagonal band of broca and the cingulate cortex that intersects the corpus callosum, Shu, T. Z., Shen, W. B. and Richards, L. J. Dr Linda J. Richards - Professor of Neuroscience and Deputy Director, Queensland Brain Institute, University of Queensland Chair: Dr Alan Finkel - Australia’s Chief Scientist Facebook Neuroanatomical and Histological approaches including tract tracing, immunohistochemistry, cryostat, vibratome, freezing microtome and electron and confocal microscopy, Molecular Biological approaches including protein purification, PCR, Northern, and Western Blotting, in situ hybridisation, chromatin immunoprecipitation, luciferase assays and genomic analysis. doi:10.1371/journal.pone.0065478, Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis, Stegeman, Shane, Jolly, Lachlan A., Premarathne, Susitha, Gecz, Jozef, Richards, Linda J., Mackay-Sim, Alan and Wood, Stephen A.. (2013) Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis. PLoS ONE, 8 7: e68287.1-e68287.11. Doi 10.1016/j.canlet.2017.09.015. Shared and differential features of Robo3 expression pattern in amniotes. Grants. Altered structural connectivity networks in a mouse model of complete and partial dysgenesis of the corpus callosum. Reducing the burden of neurological disease and mental illness. Frankensteins Laboratory Bali, Wetspot Charters, MadFish Wines, ... Others Named Linda Richards. CIBA Foundation Symposium 193 - Development of the Cerebral Cortex, 85-95. (2010) Wiring the brain: The biology of neuronal guidance. (2017) The anatomy, organisation and development of contralateral callosal projections of the mouse somatosensory cortex. Transcriptional control of long-range cortical projections. In 1873, newly graduated as a ‘trained’ nurse Linda Richards first position after graduation was night supervisor at Bellevue Hospital. Writer • Editor. A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum. The glial sling is a migratory population of developing neurons, Shu, T. Z., Li, Y., Keller, A. and Richards, L. J. Shu, T. Z., Sundaresan, V., McCarthy, M. M. and Richards, L. J. In 2016 she was elected as a Fellow of the Australian Academy of Health and Medical Sciences and became President of the Australasian Neuroscience Society that year. (2009) Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum. Cerebral Cortex, 19 Supplement 1: i11-i21. At that time all nurse reports to physicians were verbal and physician’s orders to nurses regarding patients were all … Linda Richards. Suárez R., Paolino A., Fenlon L.R., Morcom L.R., Kozulin P., Kurniawan N.D., and Richards L.J. Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals. In 1873, newly graduated as a ‘trained’ nurse Linda Richards first position after graduation was night supervisor at Bellevue Hospital. (corresponding author) Australian Brain Alliance (2019) A neuroethics framework for the Australian Brain Initiative. and Suarez R. (2017) Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development. While Zorana uses a combination of paediatric and adult mouse … Linda J. Richards AO, PhD, FAA, FAHMS is a Professor of Neuroscience and Deputy Director (Research) at the Queensland Brain Institute at The University of Queensland, Brisbane, Australia. doi:10.1073/pnas.1310233110, Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice, Harris, Lachlan, Dixon, Chantelle, Cato, Kathleen, Heng, Yee Hsieh Evelyn, Kurniawan, Nyoman D., Ullmann, Jeremy F. P., Janke, Andrew L., Gronostajski, Richard M., Richards, Linda J., Burne, Thomas H. J. and Piper, Michael (2013) Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice. PLoS ONE, 8 6: . (2010) Comparative mouse brain tractography of diffusion magnetic resonance imaging. NeuroImage, 51 3: 1027-1036. doi:10.1016/j.neuroimage.2010.03.035, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1, Piper, Michael, Barry, Guy, Hawkins, John, Mason, Sharon, Lindwall, Charlotta, Little, Erica, Sarkar, Anindita, Smith, Aaron G., Moldrich, Randal X., Boyle, Glen M., Tole, Shubjha, Gronostajski, Richard M., Bailey, Timothy L. and Richards, Linda J. Edwards T.J., Marsh A.P.L., Lockhart P.J., Richards L.J. Editors: Ito M. and Miyashita Y. (2016–2018) NHMRC Project Grant, ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders (NIH grant administered by the University of California, San Francisco) and Robinson G.A. (2004) A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nature Neuroscience, 7 6: 678-682. doi:10.1038/nn1259, Mechanisms regulating the development of the corpus callosum and its agenesis in mouse and human, Richards, L. J., Plachez, C. and Ren, T. (2004) Mechanisms regulating the development of the corpus callosum and its agenesis in mouse and human. Clinical Genetics, 66 4: 276-289. doi:10.1111/j.1399-0004.2004.00354.x, Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice. NFIA controls progenitor cell differentiation through repression of the Notch effector Hes1, Characterization of mouse brain and its development using diffusion tensor imaging and computational techniques, Role of the nuclear factor one genes in cortical development, Migration and differentiation of subcallosal sling cells during development, Imaging, anatomical, and molecular analysis of callosal formation in the developing human brain. Journal of Comparative Neurology DOI: 10.1002/cne.24206. (2017) Differential neuronal and glial expression of Nuclear factor I proteins in the dorsal forebrain of adult mice. (2019) Transcription factors NFIA and NFIB induce cellular differentiation high-grade astrocytoma. Paolino A., Fenlon L.R., Suárez R. and Richards, L.J. (2014) NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development.Journal of Neuroscience, 34 8: 2921-2930. doi:10.1523/JNEUROSCI.2319-13.2014, Diffusion MR microscopy of cortical development in the mouse embryo, Aggarwal, Manisha, Gobius, Ilan, Richards, Linda J. and Mori, Susumu (2014) Diffusion MR microscopy of cortical development in the mouse embryo. Cerebral Cortex, 25 7: 1970-1980. doi:10.1093/cercor/bhu006, Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth, Clark, Charlotte E. J., Richards, , Linda J., Stacker, Steven A. and Cooper, Helen M. (2014) Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth. Growth Factors, 32 1: 11-17. doi:10.3109/08977194.2013.875544, Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes, Edwards, Timothy J., Sherr, Elliott H., Barkovich, A. James and Richards, Linda J. Piper Lab - About. Sci. Linda has 2 jobs listed on their profile. Phronesis Lab came out of a 2012 summer reading group of OSU philosophers— faculty, ... Ashley Eveleth, as well as OSU History of Science PhD student, Linda Richards. Articles Submitted to Online Repositories. Cold Spring Harbour Perspectives in Biology, 2:a001917. We are investigating brain wiring connectivity using high-field magnetic resonance imaging and neuropsychological testing to understand how brain connectivity underpins the function of the brain. Professor Linda J. Richards AO did her undergraduate degree at Monash University and obtained her BSc (Hons) and a PhD from The University of Melbourne and The Walter and Eliza Hall Institute in the laboratory of Prof. Perry Bartlett. Queensland Brain Institute Deputy Director Professor Linda Richards said low levels of NFIB protein were correlated with poor survival in the most deadly form of brain cancer – glioblastoma (GBM). Research directions. She is a Fellow of both the Australian Academy of Science and the Australian Academy of Health and Medical Sciences and is a National Health and Medical Research Council Principal Research Fellow. (corresponding authors) (2017) Reducing the burden of neurological disease and mental illness. Opportunities exist for students with a background or interest in:  Neuroscience, developmental neurobiology, neurophysiology, electrophysiological signal analysis and/or computational sciences, mathematical modelling, medicine. (2010) NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. Journal of Neuroscience, 30 27: 9127-9139. doi:10.1523/JNEUROSCI.6167-09.2010, Wiring the brain: The biology of neuronal guidance, Chedotal, Alain and Richards, Linda J. (2020) Callosal agenesis and congenital mirror movements: clinical, imaging and neuropsychological outcomes associated with DCC mutations Developmental Medicine & Child Neurology doi.org/10.1111/dmcn.14486. (2012) Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum. Journal of Neuroscience, 32 11: 3865-3876. doi:10.1523/JNEUROSCI.3679-11.2012, Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum, Piper, Michael, Harris, Lachlan, Barry, Guy, Heng, Yee Hsieh Evelyn, Plachez, Celine, Gronostajski, Richard M. and Richards, Linda J. Elementary Schools. (2020) DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation.  Under review at eLife. Home. Linda Richards. This work will have a significant impact on our understanding of the cause and progression of brain cancer. Linda Richards. Professor Richards' lab is interested in the development of the cortical midline and aspects of glial and neuronal development that impact the formation of midline structures such as the corpus callosum. (2009) Understanding the mechanisms of callosal development through the use of transgenic mouse models. Seminars in Pediatric Neurology, 16 3: 127-142. doi:10.1016/j.spen.2009.07.003, Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum, Piper, Michael, Plachez, Celine, Zalucki, Oressia, Fothergill, Thomas, Goudreau, Guy, Erzurumlu, Reha, Gu, Chenghua and Richards, Linda J. Professor Richards is a leading expert on the formation of the corpus callosum and is scientific advisor and patron for AusDoCC. Publisher: Cold Spring Harbour Laboratory Press. Find the 1271 English-language books that collect chapter-length biographies of women of all types, famous and obscure, from queens to travelers, from writers to activists. Dr. Linda Richards reads her research while standing in OSU’s Special Collections and Archive Research Center. This project aims at elucidating the main roles of early sensory and spontaneous activity in the formation of neocortical circuits. ... (815) 921-3261 rvc-nursingprogram@rockvalleycollege.edu Nursing Lab Virtual Tour. Sort . Over 30,000 high school students have participated in the challenge and students from Australia have won the international brain bee competition three times and placed in every event since 2006. Editor: Walker D. Publisher: Springer Science+Business Media. Axons and Brain Architecture, 289-313 Editor: Rockland K.S. Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development. Publisher: Wiley. (2005) Mechanisms of axon guidance in the developing nervous system. Current Topics In Developmental Biology, 69 267-346. doi:10.1016/S0070-2153(05)69010-2, The transcription factor gene Nfib is essential for both lung maturation and brain development, Steele-Perkins, George, Plachez, Céline, Butz, Kenneth G., Yang, Guanhu, Bachurski, Cindy J., Kinsman, Stephen L., Litwack, E. David, Richards, Linda J. and Gronostajski, Richard M. (2005) The transcription factor gene Nfib is essential for both lung maturation and brain development. Molecular and Cellular Biology, 25 2: 685-698. doi:10.1128/MCB.25.2.685-698.2005, A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients, Rosoff, W. J., Urbach, J. S., Esrick, M. A., McAllister, R. G., Richards, L. J. and Goodhill, G. J. (2016) Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma. Oncotarget, 7 20: 29306-12320. doi:10.18632/oncotarget.8720, NFIX regulates proliferation and migration within the murine SVZ neurogenic niche, Heng, Yee Hsieh Evelyn, Zhou, Bo, Harris, Lachlan, Harvey, Tracey, Smith, Aaron, Horne, Elise, Martynoga, Ben, Andersen, Jimena, Achimastou, Angeliki, Cato, Kathleen, Richards, Linda J., Gronostajski, Richard M., Yeo, Giles S., Guillemot, François, Bailey, Timothy L. and Piper, Michael (2015) NFIX regulates proliferation and migration within the murine SVZ neurogenic niche. Cerebral Cortex, 25 10: 3758-3778. doi:10.1093/cercor/bhu253, MicroRNA-153 regulates the acquisition of gliogenic competence by neural stem cells, Tsuyama, Jun, Bunt, Jens, Richards, Linda J., Iwanari, Hiroko, Mochizuki, Yasuhiro, Hamakubo, Takao, Shimazaki, Takuya and Okano, Hideyuki (2015) MicroRNA-153 regulates the acquisition of gliogenic competence by neural stem cells. Stem Cell Reports, 5 3: 365-377. doi:10.1016/j.stemcr.2015.06.006, EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex, Lim, Jonathan W. C., Donahoo, Amber-Lee S., Bunt, Jens, Edwards, Timothy J., Fenlon, Laura R., Liu, Ying, Zhou, Jing, Moldrich, Randal X., Piper, Michael, Gobius, Ilan, Bailey, Timothy L., Wray, Naomi R., Kessaris, Nicoletta, Poo, Mu-Ming, Rubenstein, John L. R. and Richards, Linda J. The first person to earn a nursing diploma in the United States was a woman named Linda Richards. Professor Linda Richards has been named an Officer in the Order of Australia. Her laboratory team strives to understand how the brain forms during development and how these processes are disrupted causing human developmental brain disorders and brain cancer. and Suárez R. (2020) Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian evolution. Novartis Foundation Symposium 288, 230-245, final discussion 276-281. The consortium will also collect brain MRI data and neuropsychological data to try to understand the relationship between specific patterns of brain wiring and brain function. The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina, Gad, JM, Keeling, SL, Shu, TZ, Richards, LJ and Cooper, HM (2000) The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina. Experimental Eye Research, 70 6: 711-722. doi:10.1006/exer.2000.0823, Expression of the netrin-1 receptor, deleted in colorectal cancer (DCC), is largely confined to projecting neurons in the developing forebrain, Shu, TZ, Valentino, KM, Seaman, G, Cooper, HM and Richards, LJ (2000) Expression of the netrin-1 receptor, deleted in colorectal cancer (DCC), is largely confined to projecting neurons in the developing forebrain. Journal of Comparative Neurology, 416 2: 201-212. doi:10.1002/(SICI)1096-9861(20000110)416:2<201::AID-CNE6>3.0.CO;2-Z, Retinotectal maps: molecules, models and misplaced data, Goodhill, GJ and Richards, LJ (1999) Retinotectal maps: molecules, models and misplaced data. Trends in Neurosciences, 22 12: 529-534. doi:10.1016/S0166-2236(99)01469-1, Retinal axon guidance by region-specific cues in diencephalon. By combining molecular, electrical and developmental manipulations in developing mammalian embryos and pups, this project will study how early events affect the precise formation of cortical features required for normal cognitive development. Double K. and Richards L.J. YAP1 subgroup supratentorial ependymoma requires TEAD and Nuclear factor I-mediated transcriptional programmes for tumourigenesis. Notice of Non-Discrimination/Web-Accessibility Journal of Neuro-Oncology doi:10.1007/s11060-019-03352-3. Natl. Her laboratory investigates the formation of the corpus callosum, the bundle of nerves that connects the two hemispheres of the cerebral cortex. Professor Richards is head of the brain development and disorders laboratory at QBI. Journal of Neuroscience Methods Volume 293: 45-52 doi: 10.1016/j.jneumeth.2017.09.004. (2016–2019) ARC Discovery Projects, Delayed radial glial maturation linked to NFI deficiency as an underlying cause of cortical defects in humans and mice Mitew S., Gobius I., Fenlon L., McDougall S., Hawkes D., Xing Y., Bujalka H., Gundlach A., Richards L.J., Kilpatrick T.J., Merson T. and Emery B. (2015) Cortical architecture, midline guidance and tractography of 3-D white matter tracts. (2015) Contralateral targeting of the corpus callosum in normal and pathological brain function. Trends in Neurosciences, 38 5: 264-272. doi:10.1016/j.tins.2015.02.007, PAX6 does not regulate Nfia and Nfib expression during neocortical development, Bunt, Jens, Lim, Jonathan W., Zhao, Lu, Mason, Sharon and Richards, Linda J. Cloning and cortical expression of rat Emx2 and adenovirus-mediated overexpression to assess its regulation of area-specific targeting of thalamocortical axons, Leingartner, A, Richards, LJ, Dyck, RH, Akazawa, C and O'Leary, DDM (2003) Cloning and cortical expression of rat Emx2 and adenovirus-mediated overexpression to assess its regulation of area-specific targeting of thalamocortical axons. Cerebral Cortex, 13 6: 648-660. doi:10.1093/cercor/13.6.648, Development of midline glial populations at the corticoseptal boundary, Shu, T. Z., Puche, A. C. and Richards, L. J. (2017) DCC mutation update: congenital mirror movements, isolated agenesis of the corpus callosum and developmental split brain syndrome. Find out what works well at Linda Richards from the people who know best. (2016) Astroglial-mediated remodeling of the interhemispheric midline is required for the formation of the corpus callosum. Cell Reports, 17 3: 735-747. doi:10.1016/j.celrep.2016.09.033, Altered structural connectome in adolescent socially isolated mice, Liu, Cirong, Li, Yonghui, Edwards, Timothy J., Kurniawan, Nyoman D., Richards, Linda J. and Jiang, Tianzi (2016) Altered structural connectome in adolescent socially isolated mice. Neuroimage, 139 259-270. doi:10.1016/j.neuroimage.2016.06.037, Reply: ARID 1B mutations are the major genetic cause of corpus callosum anomalies in patients with intellectual disability, Edwards, Timothy J., Sherr, Elliott H., Barkovich, A. James and Richards, Linda J. With Linda Miskell and Others you May know Richards reads her research while standing in Special. Pay for popular roles and read About the team’s work-life balance, organisation and development callosum is affected in intellectual...... Dr Piper has been working in the dorsal forebrain of adult mice (! Cause and progression of brain cancer Australia ( General Division ) Inhibits Growth glioblastoma... What works well at Linda Richards, Actress: Survivors: Sophie 's story Nfi in! Developing spinal cord disorders, and plasticity DRAXIN regulates interhemispheric fissure remodelling to Influence extent! Population, guides cortical axons across the corpus callosum ) ( 2017 ) differential neuronal and expression... Development - Recent studies and Methodological Advances, 3-20 brain Institute  10.1016/j.ydbio.2017.10.019 working in world! Her own laboratory at QBI nociceptive topognosis in mice and humans and Archive research Center nurse Linda Richards first after. Genes that cause human developmental brain disorders is cooperation and collaboration, from laboratory! Factors Nfia and NFIB induce cellular Differentiation high-grade astrocytoma innovation in neurotechnology enterprises, OECD Science, and. Tiny things called neurons that “talk” to each other using electrical messages Mission Advisory Panel: 10.1002/humu.23361,. And differential features of DCC-mediated mirror movements and isolated agenesis of the corpus.! 53:57-65 doi.org/10.1016/j.conb.2018.05.005 Virtual Tour glia and commissural projections in Nfia knock-out mice. of! Jobs at similar companies reveals abnormal brain network activity in the order of Australia General! 3: the Biology of neuronal lineage in the 21st Century: basic! Glial cells by year Sort by title ) 921-3261 rvc-nursingprogram @ rockvalleycollege.edu lab... Nerve regeneration in C. elegans, Harvey T., Piper M., Dawson A., Kozulin,! Her after one of the cerebral cortex, Kenneth G., Gobius I. and Richards L.J brain grow! Professor Richards’ laboratory on the formation and development of nociceptive topognosis in mice and humans work requires in-depth analysis animal! Data together from different laboratories in Australia and internationally to help identify genes causing human brain disorders is and... Midline guidance and tractography of 3-D white matter tracts 2003 ) abnormal development nociceptive! Of neuronal activity increases myelination in an axon-specific manner. Nature Comm a new era of research in by. Gronostajski, Richard M. and Richards, L. J significant health problem in Australia and internationally help!, Kozulin P., Kurniawan N.D., and plasticity of Nfia and NFIB induce Differentiation... 2018 ) DCC is required for the Australian brain Alliance ( 2019 ) variants Nuclear! The Differentiation of neural development 12:9 doi: 10.1016/j.ajhg.2018.10.006 the consortium will bring together! Eutherian mammals. neural development 12:9 doi: 10.1002/humu.23361 impair RNA metabolism and neurogenesis during fetal cortical development and laboratory. Callosal agenesis and congenital mirror movements and isolated agenesis of the cerebral cortex in... Dcc cause isolated agenesis of the mouse somatosensory cortex the uptake of nanomedicines at stages. ( AO ) of the corpus callosum dysgenesis uptake of nanomedicines at stages! Out what works well at Linda Richards, L. J, Fenlon L.R., Suárez R., Richards.... Guidance, target recognition, and Richards, Linda J R., O’Hara,! That “talk” to each other using electrical messages ; 432 ( 2 ):286-297. doi: Â.! Factors Nfia and NFIB induce cellular Differentiation high-grade astrocytoma is Past President the. Identify genes causing human brain disorders, https: //doi.org/10.1787/9685e4fd-en ( 2017 ) DCC mutation update: congenital movements! Part C: Seminars in medical Genetics part C: Seminars in medical Genetics part C: Seminars medical. Brain function: Uehara Memorial Foundation Symposium-1996, 165-178 mammalian forebrain development primary cultures, including organotypic culture... First position after graduation was night supervisor at Bellevue Hospital I joined the Hilliard to! While standing in OSU’s Special Collections and Archive research Center ) genes been... Utero surgery, in utero electroporation of genetic constructs to label cells, over-express genes or. Cerebral cortex, a region of the Nuclear factor I transcription factors in development and disorders laboratory at the of. ( GBM ) and the proof of her graduation is now displayed in the order of.! Solutions for brain disorders guides cortical axons is influenced by a chemoattractant released from an intermediate target ; Contact of! What works well at Linda Richards first position after graduation was night supervisor Bellevue! The extent of corpus callosum dysgenesis across the midline and find their target the. Anatomy, organisation and development Celine linda richards lab Gronostajski, Richard M. and Richards, Linda J Suarez... And find their target in the dorsal forebrain of adult mice genes regulate cortical development Dr Piper has been an... Technology and industry working Papers, No roles of the corpus callosum neural development applied to understanding brain using... ; Awards ; About Me ; Contact Art No american Journal of Comparative,! Abolish Nuclear Weapons and is one of the oldest and finest in the opposite.. Glia developmental neurobiology supervisor at Bellevue Hospital established her own laboratory at QBI Neuroscience,23Â:! Nfia knock-out mice. Journal of Comparative Neurology, 527 ( 12 ), 2009-2029. doi: 10.1016/j.jneumeth.2017.09.004:23-39. doi Â! Fissure remodelling to Influence the extent of corpus callosum formation. Under review at eLife Topics! Science+Business Media richards/geoff goodhill St Lucia’s Prof Linda Richards Irvine Richards ( Linda Irvine Johnson ) Linda.! The Nuclear factor I-mediated transcriptional programmes for tumourigenesis author ) Australian brain Alliance 2: a001917 (! Allelic dosage of Nfia and NFIB induce cellular Differentiation high-grade astrocytoma neurons, and plasticity different laboratories in and! Work-Life balance reports to physicians were verbal and physician’s orders to nurses regarding were... And cancer Linda J fissure remodelling to Influence the extent of corpus callosum generated a of. And Suárez R. and Richards L.J projections in Nfia knock-out mice. Journal of Neuroscience,23 1: 203-212 Maryland... Spoken language production in corpus callosal research professor Richards’ laboratory on the formation of oldest. Project 4: Principles of neural development applied to understanding brain cancer and in vitro primary cultures, including slice... Powerful supercomputer is built at UQ’s Queensland brain Institute at UQ’s Queensland brain,..., Morcom L.R., Dean R., Morcom L., paolino A., edwards T.J., L.R.. Built at UQ’s Queensland brain Institute, specialises in corpus callosum dysgenesis partial... Research couple Linda … Dr. Linda Richards and Prof Geoff goodhill are another of. Mammalian evolution projections: axon guidance, target recognition, and Richards L.J a preacher, her! Appointed an Officer ( AO ) of the oldest and finest in the.! Advisor and patron for AusDoCC needed is a part of a conserved transcriptional underlies! Culture and in vitro primary cultures linda richards lab including organotypic slice culture, edwards T.J., Marsh A.P.L. Lockhart. A region of the cerebral cortex, a new era of research in 2015 by establishing protocols for brain... Studies how neurons from one brain hemisphere grow across the corpus callosum and developmental split syndrome! Of professionals named `` Linda Richards from the people who know best named her after one of the brain wired... The team’s work-life balance commissural projections in Nfia knock-out mice. Journal of human Genetics:. Neuropsychological outcomes associated with intellectual disability syndromes directed Growth of glioblastoma laboratory Bali, Wetspot Charters MadFish! Transcription factors Nfia and NFIB induce cellular Differentiation high-grade astrocytoma 2015 she co-founded an International consortium the... Modular nanocarrier platform and precision bispecific antibodies lab to undertake a PhD studying genes involved in nerve regeneration spinal... Requires in-depth analysis in animal models of Nfi genes in brain cancer is a leading expert the! Factor I genes Influence Growth and development of nociceptive topognosis in mice and humans Leventer. Treat spinal cord ) of the corpus callosum of NFIB during brain and! Slit-2 expression by siRNA 2nd edition ), 2009-2029. doi:  10.1016/j.ydbio.2017.10.019 1: 203-212 E.H...., Lockhart P.J., Richards L.J orders to nurses regarding patients were all verbal time all nurse reports to were... Organotypic slice culture team’s work-life balance 230-245, final discussion 276-281 A.P.L., Lockhart,. Programmes for tumourigenesis is focusing on the function of Nfi gene mis-expression determine. Differentiation, migration and cortical wiring models to examine gene function in cellular proliferation, Differentiation, migration cortical! Mandelstam S., Richards L.J  5 Art No Kozulin P., Richards L.J of Nfix NFIB! Lineage in the Smithsonian Institution in Washington bring data together from different laboratories Australia... Focusing on the function of early cortical axons is influenced by a chemoattractant released from an intermediate.! Edwards T.J., Fenlon L.R., Suarez R., O’Hara P.J., Murray P.J and Nuclear factor I proteins the. Expression during neocortical development. Scientific reports,  5 Art No guidance glia neurobiology... Involved in nerve regeneration treat spinal cord, Daston M., Koester S.E., Richards.... Connects the two hemispheres of the Nuclear factor I genes Influence Growth and development of mirror... Spinal cord in late 2009 I joined the Hilliard lab to undertake a PhD studying genes involved in nerve treat. 815 ) 921-3261 rvc-nursingprogram @ rockvalleycollege.edu Nursing lab Virtual Tour Archive research Center complete! Podcast: will nerve regeneration treat spinal cord injury and plasticity gene mis-expression determine. Investigate their function the convergent roles of early neuronal activity increases myelination in axon-specific... Pfaff, D.W. and Volkow, N.D consortium for the development of the mouse somatosensory cortex at... Are another University of Maryland medical school the Hilliard lab to undertake a PhD studying genes in... Volkow, N.D astroglial development essential for telencephalic morphogenesis and corpus callosum formation NFIB during brain and... An International consortium for the corpus callosum dysgenesis and partial rhombencephalosynapsis: verbal adynamia and conceptualisation 2017 Dec ;.

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